LYSE S III diff Lytic Reagent is used as a lytic agent to prepare a diluted whole-blood sample for the quantitative determination of hemoglobin, the enumeration of leukocytes (white blood cells), and the derivation of leukocyte subpopulations.

For use as an erythrocyte lytic agent for the quantitative determination of hemoglobin and for leukocyte counting and sizing on COULTER JT Series, GEN•S, STKS, MAXM, HmX, LH 500, LH 750, and LH 780 hematology analyzers. Use with only ISOTON III or LH Series diluent.