CEO-TWO Laxative Suppositories combine Sodium Bicarbonate and Potassium Bitartrate in Polyethylene Glycol Base.  Upon insertion into the rectum, the pre-moistened suppository reacts with the moisture present to produce carbon dioxide gas.  This CO2 gas gently expands the lower bowel and creates a reflex stimulation resulting in an urge to empty the lower bowel within 30 minutes.  Moreover, there is no chemical stimulation to the bowel, no painful cramping, no diarrhea and rarely a second urge to defecate.